MicroRNAs and Alzheimer's Disease
Alzheimer's disease clinical-pathological studies. 3. MiRNAs in . B. Work in Alzheimer's disease . mRNA is ~5% of total cellular RNA and is poorly correlated .
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Targeting Alzheimer's disease genes with RNA interference: an ...
Here, using tau and APP as model targets, we describe an efficient method for producing small interfering RNA (siRNA) against essentially any targeted region .
Noncoding RNA may promote Alzheimer's disease
Jun 20, 2011 . Researchers pinpoint a small RNA that spurs cells to manufacture a particular splice variant of a key neuronal protein, potentially promoting .
RNA profiling in an Alzheimer's disease mouse model
Title: RNA profiling in an Alzheimer's disease mouse model. Author: Bao, Hongbo, 1977-. Abstract: Alzheimer's disease (AD) is one of the common diseases of .
Alzheimer's Disease | RNA-Seq Blog
IPA was used to interpret Alzheimer's disease biology by comparing Illumina RNA-Seq data from Alzheimer's disease (AD) and normal brain samples.
Researchers Find Role RNA Plays In Progress Of Alzheimer's Disease
Nov 5, 2003 . The study found that oxidation a type of damage to cells caused by free radicals can damage certain kinds of messenger RNA in the brain.
Neuroscience Faculty Member - Michael Wolfe
A related project is focused on RNA splicing of beta-secretase, which along with gamma-secretase produces the neurotoxic amyloid-beta peptide of Alzheimer's .
BU Team IDs RNA-Binding Proteins as Potential Alzheimer's ...
Jun 22, 2012 . A research team led by scientists at Boston University has identified several RNA -binding proteins as potential therapeutic targets and .
A micro-RNA as a key regulator of learning and Alzheimer's disease
Sep 25, 2011 . Scientists have identified an RNA molecule as a potential target for new Alzheimer's therapies.
Dendritic BC200 RNA in aging and in Alzheimer's disease
Jun 19, 2007 . Abstract. Small untranslated BC1 and BC200 RNAs are translational regulators that are selectively targeted to somatodendritic domains of .
RNA Binding Proteins in Alzheimer's Disease
Jul 1, 2012 . Non-Technical Title: RNA Binding Proteins in Alzheimer's Disease. Acknowledgements: The grant was made possible due to a generous .
Alzheimer's PAXGene / RNA | PrecisionMed, Inc.
PrecisionMed has availability of PAXGene/RNA from donors with Alzheimer's disease. PAXGene/RNA samples are from donors with Alzheimer's disease and .
Spreading of Alzheimer's disease inflammatory signaling through ...
Jul 11, 2012 . Spreading of Alzheimer's disease inflammatory signaling through soluble micro- RNA. Lukiw WJ, Alexandrov PN, Zhao Y, Hill JM, Bhattacharjee .
NSF REU Site: Summer program in the biochemical sciences
Steven Estus, RNA splicing of genes related to cholesterol homeostasis and Alzheimers disease. The goal of this project is to (i) identify novel splice variants in .
IPA: Using IPA to analyze RNA-Seq data in Alzheimer's Disease ...
Dec 15, 2011 . Presented by Darryl Gietzen, Ph.D., Ingenuity Systems IPA was used to interpret Alzheimer's disease biology by comparing Illumina RNA-Seq .
Alzheimer's Disease Brain: Alterations in RNA Levels and in a ...
20. W. D. Sutton, W. L. Gerlach, D. Schwartz, W. J. Peacock, Science 223, 1265 ( 1984). 21. L. H. Soe, B. G. Devi, J. I. Mullins, P. Roy-. Burman. J. Virol. 46, 829 .
The Identification and Characterization of Oxidized RNAs in ...
It has been shown that cytoplasmic RNA oxidation occurs to a great extent in the brains of Alzheimer's disease (AD) patients. The goal of this study was to isolate .
New Group of Proteins in the Brains of Alzheimer's Patients ...
Jun 13, 2012 . Alzheimer's disease is presumed to be caused by the accumulation of . A different RNA binding protein, G3BP, accumulates primarily in .
Regulatory RNA goes awry in Alzheimer's disease : Article : Nature ...
May 15, 2008 . This BACE1 antisense RNA is also elevated in Alzheimer's diseaseaffected brain, causes upregulation of BACE1 expression by stabilizing .
Long noncoding RNAs: functional surprises from the RNA world
Although the vast majority of long noncoding RNAs have yet to be . (2008) Expression of a noncoding RNA is elevated in Alzheimer's disease and drives .